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How can DHEA supplementation support immune function?

DHEA, or dehydroepiandrosterone, is a hormone produced by the adrenal glands. It plays a crucial role in various bodily functions, including immune system regulation. DHEA levels naturally decline with age, and this decline has been associated with a weakened immune system.

Supplementing with DHEA has been shown to have several benefits for immune function. Here are some ways in which DHEA supplementation can support the immune system:

1. Enhancing T-cell function:

T-cells are a type of white blood cell that plays a vital role in immune response. DHEA has been found to enhance the function of T-cells, improving their ability to recognize and destroy pathogens.

2. Modulating cytokine production:

Cytokines are small proteins that regulate immune responses. DHEA supplementation has been shown to modulate cytokine production, promoting a balanced immune response and reducing excessive inflammation.

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3. Boosting natural killer cell activity:

Natural killer (NK) cells are another type of white blood cell that plays a crucial role in immune surveillance and defense against viruses and cancer cells. DHEA supplementation has been found to enhance NK cell activity, improving the body’s ability to fight off infections and tumors.

4. Supporting thymus function:

The thymus gland is responsible for the development and maturation of T-cells. As we age, the thymus gland shrinks, leading to a decline in T-cell production. DHEA supplementation has been shown to support thymus function, promoting the production of new T-cells and maintaining a healthy immune system.

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5. Reducing oxidative stress:

Oxidative stress, caused by an imbalance between free radicals and antioxidants in the body, can impair immune function. DHEA has antioxidant properties and can help reduce oxidative stress, thereby supporting immune health.

It is important to note that while DHEA supplementation may have potential benefits for immune function, it is always recommended to consult with a healthcare professional before starting any new supplement regimen. They can provide personalized advice based on your specific health needs and help determine the appropriate dosage and duration of supplementation.

Keywords: immune, function, supplementation, system, production, thymus, support, decline, oxidative