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Can DHEA help improve cognitive function in older adults?

DHEA, also known as dehydroepiandrosterone, is a hormone produced by the adrenal glands. It is a precursor to both estrogen and testosterone and plays a crucial role in various bodily functions. As individuals age, the levels of DHEA in the body naturally decline.

There has been significant interest in the potential benefits of DHEA supplementation, particularly in relation to cognitive function in older adults. Several studies have explored the effects of DHEA on memory, attention, and overall cognitive performance.

Evidence supporting the cognitive benefits of DHEA

Research suggests that DHEA supplementation may have positive effects on cognitive function in older adults. A study published in the Journal of Clinical Psychopharmacology found that DHEA supplementation improved verbal fluency and working memory in healthy older individuals.

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Another study published in the Journal of Clinical Endocrinology and Metabolism examined the effects of DHEA supplementation on cognitive function in older adults with mild cognitive impairment. The results showed that DHEA supplementation led to improvements in memory and executive function.

Mechanisms of action

The exact mechanisms through which DHEA improves cognitive function are not fully understood. However, it is believed that DHEA may exert its effects by influencing neurotransmitter systems, such as increasing dopamine and serotonin levels in the brain. Additionally, DHEA may have neuroprotective properties and promote the growth of new neurons.

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Considerations and limitations

While the evidence suggests potential cognitive benefits of DHEA supplementation, it is important to consider certain limitations. The studies conducted so far have been relatively small in scale, and more research is needed to establish the efficacy and safety of DHEA for cognitive enhancement in older adults.

Furthermore, individual responses to DHEA supplementation may vary, and it is essential to consult with a healthcare professional before starting any new supplement regimen. DHEA supplementation may also have potential side effects, including hormonal imbalances, acne, and hair loss.

Conclusion

In conclusion, DHEA supplementation shows promise in improving cognitive function in older adults. While more research is needed to establish its efficacy and safety, the existing evidence suggests potential benefits. It is important to approach DHEA supplementation with caution and consult with a healthcare professional for personalized advice.

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Keywords: cognitive, supplementation, function, adults, effects, potential, benefits, memory, evidence