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Are there any studies supporting the use of Metformin for longevity?
Are there any studies supporting the use of Metformin for longevity?-November 2024
Nov 21, 2024 1:22 PM

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Are there any studies supporting the use of Metformin for longevity?

Metformin is a commonly prescribed medication for the treatment of type 2 diabetes. However, in recent years, there has been growing interest in its potential role in promoting longevity and delaying age-related diseases.

Several studies have investigated the effects of Metformin on lifespan and healthspan in various model organisms, including worms, flies, and mice. These studies have shown promising results, suggesting that Metformin may indeed have anti-aging properties.

One notable study conducted by the Barzilai lab at the Albert Einstein College of Medicine involved the use of Metformin in a group of individuals with diabetes. The study found that individuals taking Metformin had a significantly lower risk of age-related diseases, such as cardiovascular disease and cancer, compared to those not taking the medication. Furthermore, the study also found that Metformin users had a slightly longer lifespan compared to non-users.

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Another study published in the journal Nature Communications investigated the effects of Metformin on the lifespan of C. elegans, a commonly used model organism in aging research. The study found that Metformin treatment extended the lifespan of the worms by up to 20%. Additionally, the worms treated with Metformin also exhibited improved healthspan, with delayed age-related decline in mobility and fertility.

While these studies provide promising evidence for the potential longevity benefits of Metformin, it is important to note that more research is needed to fully understand its mechanisms of action and its effects on human lifespan. Currently, there are ongoing clinical trials, such as the Targeting Aging with Metformin (TAME) trial, which aim to further investigate the effects of Metformin on aging and age-related diseases in humans.

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In conclusion, while there are studies supporting the use of Metformin for promoting longevity, further research is needed to establish its efficacy and safety in humans. It is always recommended to consult with a healthcare professional before considering any medication or intervention for longevity purposes.

Keywords: metformin, studies, longevity, lifespan, related, effects, medication, diseases, research

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